关键词: 煤尘提取物, 遗传毒性, 亚硝化, 致突变, 挥发分

Abstract: In this research ,sixteen coal samples including seven kinds of coals in Shanxi province was investigated ,which including : bituminous coal stome , coal carbonization ,gas coal ,etc. Each coal sample ext ract was divided into two part s : non2nit rosated sample and nit rosated sample.Ames test ,SOS test ,doublenuiclei micronuclei test , rat bone2marrow cell chromosome aberration test indicated :among sixteen coal ext ract s ,ten were positive in Ames test ,SOS test . One or two or three samples f rom the ten positive est ract s were performed by chromosome aberration test and doublenuclei micronuclei test . Positive rate was 62. 5 %. Test s indicate large concent ration of volitile component , nit rosated ext ract s which are heavier brown liquid were mutagenic. The heavier the color was , the more mutagenic the ext ract s were ,which indicated concent ration of volatile component reflected the organic substance content s indirectly. Large concent ration volatile was in large proportion ,which appeared more mutagenic. This discovery provides a much simpler way to test the dispersible content , which can save large amount of human power and material power.

Key words: Coal Dust Ext ract s, Genotoxicity, nit rosate, Mutagenic, Volitile Component